Nonreassuring fetal status and chorioamnionitis are indications for delivery. If the patient presents with vaginal bleeding, there may be a concern for placental abruption and delivery should be considered. The decision for delivery should be made based on fetal status, amount of bleeding, the stability of the mother, and gestational age. In a term patient, if spontaneous labor does not occur near the time of presentation, labor should be induced. Generally, patients with preterm PROM should be admitted to the hospital with periodic assessment for infection, placental abruption, umbilical cord compression, fetal well-being, and labor. Periodic ultrasound evaluation should be performed to monitor fetal growth as well as periodic fetal heart rate monitoring. Vital signs should be monitored and a rise in maternal temperature should raise suspicion for an intrauterine infection. Serial monitoring of leukocytes and inflammatory markers has not proved to be useful in diagnosing infection as they are found to be nonspecific if there is no clinical evidence of infection. Administration of corticosteroids will also cause transient leukocytosis.

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